Objective To investigate the effects of lipopolysaccharide ( LPS) on Src-suppressed C Kinase Substrate ( SSeCKS) in cultured astrocytes. 目的研究细菌脂多糖(LPS)对培养的大鼠星形胶质细胞中Src抑制的蛋白激酶C的底物(SSeCKS)表达的影响。
The antibody contained many protein kinase C phosphorylation sites and casein kinase ⅱ phosphorylation sites in both the VH and VL domains. VH和VL区均有多个蛋白激酶C磷酸化位点和酪氨酸激酶Ⅱ磷酸化位点。
Effect of Protein Kinase C and Protein Kinase B on G2/ M Transition by Affecting p21 in Mouse Fertilized Eggs PKC、PKB通过p21~(CIP1/WAF1)蛋白对小鼠受精卵G2期向M期转换的影响
Cloning and sequence analysis of a gene encoding the receptor of activated protein C kinase ( rack) from Leishmania braziliensis parasites 巴西利什曼原虫激活蛋白激酶C受体的基因克隆化与序列分析
HGF antibody didn ′ t induce phosphorylation of c MET tyrosine kinase. 抗HGF抗体不诱导c-MET酪氨酸激酶磷酸化。
Objective: To determine the role of cross-talk between calcineurin-dependent signal transduction pathway and protein kinase C ( PKC), mitogen-activated protein kinase ( MAPK) and protein kinase A ( PKA) in airway remodeling in asthma. 目的研究钙调神经磷酸酶(CaN)信号途径与蛋白激酶C(PKC)、丝裂素活化蛋白激酶(MAPK)和蛋白激酶A(PKA)的相互调节在哮喘气道重塑发病中的作用。
The sequence has N-glycosylation site, Protein kinase C phosphorylation site and Casein kinase II phosphorylation site. 序列中有N一糖基化位点,蛋白激酶C磷酸化位点和酪蛋白激酶11磷酸化位点;
The results showed the positive relationship of AP1 and NF κ B transcriptional activity, DNA binding activity, LMP1 expression, c Jun N terminal kinase ( JNK) activity to malignancy in NPC cell lines. 结果显示恶性程度不同的SUNE1亚细胞株的反式激活活性、DNA结合活性、LMP1蛋白表达及CJUN氨基端激酶(JNK)活性均存在明显差异,且与细胞恶性程度正相关。
Objective To observe the activity of c Jun N terminal kinase/ stress activated protein kinase ( JNK/ SAPK) and assess the correlation between JNK/ SAPK activity and ICAM 1 expression on mesangial cells in mesangial proliferative glomerulonephritis ( MSPGN). 目的检测体外培养的系膜增生性肾小球肾炎(MSPGN)肾小球系膜细胞的JNK/SAPK活性,并探讨其对细胞间粘附分子1(ICAM-1)的调控作用。
Objective: To investigate the effects of diet consistency on the expression of neurotrophin-3 ( NT-3), and it's receptors tyrosine kinase C ( TrkC) in the rat masseter muscle during different development periods. 目的:检测不同硬度食物喂养下,大鼠在离乳后不同发育阶段咬肌神经营养因子3(Neurotrophin-3,NT-3)及其受体酪氨酸蛋白激酶C(tyrosinekinaseC,TrkC)的表达变化。
The c-RAF-1 protein kinase was highly phosphorylated in the resistant cells, which might be associated with multidrug resistance and resistance to apoptosis. 抗性细胞内c-RAF-1蛋白激酶磷酸化程度明显提高,可能与多药抗药性和抗细胞调亡有关。
This article briefly reviews the regulative effects of these signaling pathways including protein kinase C, mitogen activated protein kinase, and phosphoinositide 3 '-OH kinase/ protein kinase B. 本文简要介绍心肌细胞内皮素激活蛋白激酶C、丝裂原激活蛋白激酶、磷酸肌醇3'羟基激酶/蛋白激酶B等信号通路的调节作用。
Effects of lipopolysaccharide on the expression of Src-suppressed C kinase substrate in cultured astrocytes 细菌脂多糖对培养星形胶质细胞中Src抑制的蛋白激酶C底物表达的影响
Protein Kinase C 、 Protei Kinase B Control G2/ M Transition in Mouse Fertilized Eggs by Affecting p21 在小鼠受精卵中PKC、PKB通过p21~(CIP1/WAF1)蛋白影响G2/M转换
Association of protein interacting with C kinase 1 polymorphism with psychosis in mixed pedigrees of Chinese Han population 汉族人群混合家系蛋白激酶C结合蛋白1基因多态与精神病的关联性
BACKGROUND: Whether plumbum ( Pb) exposure induced learning and memory disorder in animals is correlated with the changes of the activity of protein kinase C ( PKC) in the brain tissue? 背景:铅暴露引起的动物学习记忆障碍与脑细胞中蛋白激酶C(proteinkinasec,PKC)活性改变是否有关系呢?
The effect of Epstein-Barr virus infection on the activities of protein kinase C and tyrosine protein kinase in different subcellular fractions of CNE-2Z cell line in vitro Epstein-Barr病毒感染对CNE-2Z不同细胞组分中PKC和TPK活性的影响
C Src kinase activity was also obviously inhibited. c-Src激酶活性也显著抑制;
The Structure and Function of Protein Interacting with C α Kinase 蛋白激酶Ca相互作用蛋白的结构与功能
Methods: We used Takai's method to study activity of protein kinase C ( PKC) and its inhibitor ( PKCI) in oral squamous cell carcinomas and their adjacent normal tissues from twenty patients. 方法:采用Takai法研究20例口腔鳞癌及其临近正常组织的蛋白激酶C(proteinkinasec,PKC)及其抑制物(ProteinkinaseCinhibitor,PKCI)活性。
Regulatory effect of protein kinase C and protein kinase G on calcium sensitivity of vascular smooth muscle cells following hemorrhagic shock 蛋白激酶C和蛋白激酶G对失血性休克大鼠血管平滑肌细胞钙敏感性的调节作用
Molecular cloning and sequencing of human c fms-like tyrosine kinase 3 receptor ligand gene FMS样酪氨激酶3受体配基基因的克隆和序列分析
There were many protein kinase C phosphorylation sites and casein kinase II phosphorylation sites in the V_H and V_L domains. PHDsec二级结构显示CSAs-1属于α+β蛋白,VH和VL区均有多个蛋白激酶C磷酸化位点、酪蛋白激酶II磷酸化位点;
Objective To investigate the role of c Jun N terminal kinase ( JNK)-c Jun/ activator protein 1 ( AP 1) signal pathway in expression of monocyte chemoattractant protein 1 ( MCP 1) in experimental rat glomerulonephritis. 目的探讨CJUN氨基末端激酶激活蛋白1信号通路在肾小球肾炎单核细胞趋化蛋白1表达中的作用。
Objective: To evaluate the regulatory mechanisms of protein kinase C ( PKC) on adhesive and invasive effects of colorectal carcinoma cells ( HT-29) in vitro. 目的探讨蛋白激酶C(proteinkinasec,PKC)对大肠癌HT-29细胞体外粘附、侵袭能力的调控作用。
Objective To observe the effect of protein kinase C ( PKC) and protein kinase G ( PKG) on calcium desensitization following hemorrhagic shock in rats. 目的探讨蛋白激酶C(PKC)、蛋白激酶G(PKG)对失血性休克大鼠血管平滑肌细胞钙敏感性的调节作用。
Ve: To determine the expression and distribution of protein kinase C ( PKC) and apoptosis gene Bcl-2/ Bax on olfactory bulb in rats. The relationship between protein kinase C and apoptosis gene Bcl-2/ Bax were discussed. 目的:明确蛋白激酶C和凋亡相关基因Bcl-2和Bax在大鼠嗅球中的表达分布及相关性,探讨蛋白激酶C(proteinkinasec,PKC)对大鼠嗅球神经元凋亡的调节作用。
Motif search results indicate that there are a variety of N-glycosylation sites, protein kinase C phosphorylation sites, pyruvate kinase active sites and other functional domains on PK. 模体搜索结果表明在PK上具有多种N-糖基化位点、蛋白激酶C磷酸化位点、丙酮酸激酶活性位点等多个功能结构域。
Protein kinase C ( protein kinase C, PKC) is a serine/ threonine protein kinase with a single peptide chain structure, which is the central link of the body cell signaling pathways, widely distributed in the central nervous system. 蛋白激酶C(proteinkinasec,PKC)是一组具有单一肽链结构的丝氨酸/苏氨酸蛋白激酶,是机体细胞信号传导通路的中心环节,广泛分布于中枢神经系统。
In addition, G βγ dimers plays important roles on the intracellular localization, regulating receptor function, influencing the activities of phospholipase C β, receptor kinase, and adenylate cyclase. 此外,Gβγ对细胞内定位,调节受体功能,活化磷脂酶Cβ,影响受体激酶和腺苷酸环化酶活性等都起到重要作用。